Those in the treatment group were prescribed 500 mg of Naproxen twice a day. The prevalence of HO was 46% in the control group versus 4% in the naproxen group. Minor adverse reactions to the study medications were reported in 42% of the patients taking naproxen versus 35% of those taking the placebo (p = 0.45).
Comment: While the shoulder is not the hip, and femoroacetabular impingement surgery is not arthroplasty, we are interested in the use of Naproxen as a means of increasing comfort and decreasing stiffness after shoulder arthroplasty. In the past we avoided anti-inflammatory medications (NSAIDs) after shoulder arthroplasty out of concern for bleeding and delayed healing. Currently, however, Naproxen has become a part of our postoperative program. Our initial observations are that the postoperative course is smoother for the patient and we've not observed significant side effects.
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