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Showing posts with label next generation sequencing. Show all posts
Showing posts with label next generation sequencing. Show all posts
Tuesday, November 22, 2022

Should surgeons doubt the value of cultures in shoulder surgery?

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It is well recognized that bacterial infections are important causes of failed shoulder arthroplasy, failed cuff repairs and failed fracture...
Saturday, October 29, 2022

How does surgery for periprosthetic infection fail?

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Revision surgery for periprosthetic infection may fail because of (1) definite septic failure: persistence of infection after revision surg...
Tuesday, September 20, 2022

Periprosthetic infections with negative cultures - are there bacteria there? What is the value of next generation sequencing?

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The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria  is shown below. By this set of crite...
Saturday, July 9, 2022

Next generation sequencing: is this innovation of clinical value?

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Poor Agreement Between Next-Generation DNA Sequencing and Bacterial Cultures in Orthopaedic Trauma Procedures Next-generation DNA sequencing...
Saturday, December 14, 2019

Next-generation sequencing - what does it detect?

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Next-generation sequencing for diagnosis of infection: is more sensitive really better? These authors  point out that the utility of next-...
Tuesday, August 20, 2019

Shoulder infections - is there a problem with PCR?

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Polymerase chain reaction (PCR) has been advocated for the identification of organisms associated with periprosthetic shoulder infections. A...
Sunday, April 14, 2019

Detecting bacteria in revision shoulder arthroplasty: culture and next generation sequencing

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Comparative study of cultures and next-generation sequencing in the diagnosis of shoulder prosthetic joint infections In 44 patients unde...
Friday, January 25, 2019

Revision shoulder arthroplasty - what is the role of next-generation sequencing?

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Comparative study of cultures and next-generation sequencing in the diagnosis of shoulder prosthetic joint infections These authors point ...