Friday, January 8, 2016

Naproxen after joint surgery

Effect of Naproxen Prophylaxis on Heterotopic Ossification Following Hip Arthroscopy: A Double-Blind Randomized Placebo-Controlled Trial.

These authors performed a Level I study to determine the effect of postoperative naproxen therapy on the development of unwanted bone formation (HO) following arthroscopic surgery for femoroacetabular impingement.

Those in the treatment group were prescribed 500 mg of Naproxen twice a day. The prevalence of HO was 46% in the control group versus 4% in the naproxen group.  Minor adverse reactions to the study medications were reported in 42% of the patients taking naproxen versus 35% of those taking the placebo (p = 0.45).

Comment: While the shoulder is not the hip, and femoroacetabular impingement surgery is not arthroplasty, we are interested in the use of Naproxen as a means of increasing comfort and decreasing stiffness after shoulder arthroplasty. In the past we avoided anti-inflammatory medications (NSAIDs) after shoulder arthroplasty out of concern for bleeding and delayed healing. Currently, however, Naproxen has become a part of our postoperative program. Our initial observations are that the postoperative course is smoother for the patient and we've not observed significant side effects.

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