Wednesday, March 18, 2020

Risks of anticoagulation after shoulder arthroplasty

Therapeutic postoperative anticoagulation is a risk factor for wound complications, infection, and revision after shoulder arthroplasty

These authors examined the relationship between postoperative therapeutic anticoagulation, wound complications, infection, and revision using a national insurance database from 2007 to 2016

Those with a prescription for a therapeutic anticoagulant within 2 weeks of surgery were identified and compared with controls without postoperative therapeutic anticoagulant prescriptions.

A total of 17,272 patients were included, including 684 patients who received therapeutic anticoagulation and 16,588 controls.

Patients receiving therapeutic anticoagulation had increased risk of wound complications at 3 months (odds ratio [OR] 3.0, 95% confidence interval [CI] 2.0-4.6, P < .0001) and 6 months (OR 2.5, 95% CI 1.7-3.8, P < .0001).

Patients receiving therapeutic anticoagulation also experienced increased rates of wound infection at 3 months (OR 1.5, 95% CI 1.1-2.0, P ..007) and 6 months (OR 1.8, 95% CI 1.4-2.3, P <.0001).

Finally, patients receiving therapeutic anticoagulation experienced increased rates of revision surgery at 6 months (OR 1.8, 95% CI 1.3-2.5, P . .0003) and within 9 years (OR 1.5, 95% CI 1.1-2.0, P . .007).

Comment: The risks of anticoagulation are undeniable. We have found this program to be effective
(1) to ask the patient's cardiologist for each patient with atrial fibrillation if anticoagulation is really necessary - often it turns out not to be,
(2) to be meticulous about hemostasis,
(3) to use thrombogenic agents at the time of surgery (e.g. topical tranexamic acid, thrombin+gelfoam, etc),
(4) to close the wound with staples to allow drainage,
(5) to use a dressing with suction (see illustration below),
(5) to delay range of motion exercises until it is obvious that bleeding is under control, and
(6) to ask the patient and family to notify us promptly of increased swelling, pain or drainage.



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