Sebaceous secretion is low in children and begins to increase in mid- to late childhood under the influence of androgens. This rise continues until the late teens, after which no further significant change takes place until late in life.
In elderly men, sebum levels remain essentially unchanged from those of younger adults until the age of 80. In women, sebaceous secretion decreases gradually after menopause and shows no significant change after the 7th decade.
The most likely explanation for the decrease in sebaceous gland secretion with age in both men and women is a concomitant decrease in the endogenous production of androgens.
Comment: The dermal sebaceous glands are an important site of Propionibacterium. It is possible that the difference in Propionibacterium prevalence between males and females is related to the difference in sebum production between the sexes.
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