These authors sought to evaluate whether liposomal bupivacaine would provide superior pain relief for shoulder replacement patients over bupivacaine alone. Patients received two anesthetics, a general anesthetic and a block with one of the two bupivacaine formulations.
They found no clinically relevant advantage to the use of liposomal bupivacaine over plain bupivacaine. Complications from the blocks were not reported.
Comment: There is no question that narcotic pain medications place patients at risk for nausea/vomiting, respiratory depression, constipation, falling, urinary retention, and confusion.
While some authors use plexus blocks to minimize narcotics, as shown below, plexus blocks have potentially serious risks as well.
Our practice is to avoid the risks, time and cost of plexus blocks for shoulder arthroplasty. Instead, we employ preoperative education and a multimodal approach including Tylenol, Celebrex and Gabapentin. Assisted motion is started for all anatomic arthroplasties immediately after surgery in the recovery room.
With this "block-less" program our patients have minimal difficulty in starting their immediate postoperative range of motion exercises as is shown here for a 63 year old man on the morning after his ream and run arthroplasty immediately prior to his discharge.
Here is a bit more discussion regarding the issues with blocks:
In a randomized study, these authors compared continuous interscalene block (CIB) with single-shot interscalene block for postoperative control in 76 patients having shoulder arthroplasty.
Pain scores (P = 0.010) and opioid use (P = 0.003) on the first postoperative day were lower in the CIB group, but there was no difference in length of stay. Note that over half of the patients had a length of stay over one day.
*Note that the costs listed in this table do not include the professional fees for the anesthesiologist's time for performing either a single shot or a CIB.
Continuous versus single shot brachial plexus block and their relationship to discharge barriers and length of stay
These authors conducted a retrospective review of 697 patients undergoing upper extremity arthroplasty comparing the rate of complications and incidence of potential barriers to discharge and length of stay of patients receiving continuous vs. single-shot perineural brachial plexus block.
The complication rate was 12% (n=63) for the indwelling group and 17% (n=30) for the single-shot group.
Our thoughts on interscalene block anesthetics can be viewed here:
Why not just do an interscalene nerve block anesthetic?